EPR systems for alanine dosimetry

Measurement of absorbed dose to water using alanine dosimeters

DTU Dosimetry operates three electron paramagnetic resonance (EPR) spectrometers for traceable measurement of absorbed dose to water using alanine dosimeters. The technique is based on detection of stable free radicals formed in alanine during irradiation, where the absorbed dose is determined from the microwave absorption of unpaired electrons.

Alanine dosimetry is used across a wide dose range, from radiotherapy levels (~1 Gy) to high-dose radiation processing (>100 kGy) using alanine pellet dosimeters (typically ~60 mg, 4.8 mm diameter, 2.8 mm height) and alanine film dosimeters (thickness ~135 µm). Pellet dosimeters are used for high-energy photon, electron and X-ray measurements, while alanine films are applied for low-energy electron dosimetry.

The EPR systems provide high accuracy, stability and traceability, supporting both reference dosimetry and routine measurements. The systems are used in calibration, process validation, research and development, and form a central part of the laboratory’s measurement infrastructure.

 

Fact box – EPR spectrometers

  • Measurement principle:
    Electron paramagnetic resonance (EPR) of radiation-induced free radicals
  • Dosimeters used:
    • Alanine pellets (Harwell Dosimeters Ltd – Steris AST)
    • Alanine films (Kodak)
  • Dose range:
    ~1 Gy to >100 kGy (system dependent)

 

Bruker e-scan

  • Measurement range:
    • Pellets: 0.6 kGy – 120 kGy
    • Films: 1 kGy – 165 kGy
  • Installation: November 2003

 

Bruker EMX Micro

  • Measurement range:
    • Pellets: <1 Gy – 120 kGy
    • Films: Not used
  • Features: Water-cooled, nitrogen-purged waveguides
  • Installation: August 2007

 

Magnet tech / Bruker MS-5000 X

  • Measurement range:
    • Pellets: 20 Gy – 120 kGy
    • Films: 50 Gy – 165 kGy
  • Features: Nitrogen-purged waveguides
  • Installation: June 2020

Contact

Christina Ankjærgaard

Christina Ankjærgaard Head of Dosimetry, senior researcher Department of Health Technology Mobile: +45 61656929

Arne Miller

Arne Miller Specialist Consultant Department of Health Technology Mobile: 2132 5613